Louisville Football: 25 programs that have never beat the Cardinals

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Sep 26, 2015; Champaign, IL, USA; Middle Tennessee Blue Raiders quarterback Brent Stockstill (12) is pressured by Illinois Fighting Illini defensive lineman Chunky Clements (11) and defensive lineman Jihad Ward (17) during the final drive at Memorial Stadium. Illinois beat Middle Tennessee State 27-25. Mandatory Credit: Mike Granse-USA TODAY Sports /

22. Middle Tennessee State

Louisville obviously leads this series, but the Cards haven’t scored less than 42 points in the three games they have played. These two schools have played some extremely entertaining games against one another back in the mid-2000’s.

Here are some of the series stats, according to Sports Reference:

"Longest winning streak by Louisville: 3 games Most points scored by Louisville: 58 (Sep 6, 2007) Most points scored by Middle Tennessee State: 42 (Sep 6, 2007) Largest margin of victory by Louisville: +27 (Oct 6, 2006)"

It’s pretty crazy to think that Louisville is putting up C-USA type of offensive numbers this year in the ACC. Little did we know in 2007 that Brian Brohm’s offense wouldn’t be the best Louisville offense of all-time.

Next: Number 21

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