Louisville football is heading into the weekend undefeated after the Cardinals' wild come-from-behind victory over Pitt. Despite being undefeated, Jeff Brohm's Cardinals remain unranked, but all that can change with their crucial ACC showdown this weekend against the No. 24 Virginia Cavaliers.
Entering the season, Louisville fans most likely weren't circling this showdown as a crucial game. However, after UVA started 4-1 in 2025, including a massive win over Florida State, this is all of a sudden a must-win game for Louisville.
The Cardinals and Cavaliers are both trying to make some noise in this wide-open ACC race, making Saturday have massive implications for both football teams. Both teams are coming off huge wins and are likely to be emotionally charged as they enter Saturday.
So, with Louisville fans eager for the game this Saturday, here are three crucial keys for the Louisville Cardinals to upset the No. 24 Virginia Cavaliers.