5 burning questions that will make or break Louisville football’s 2025 season

Louisville football must answer these five questions before the 2025 season.
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5 of 5

1. Can Louisville make it to the CFP?

Yes. This Louisville team can 100 percent crash the College Football Playoffs. However, it will be challenging. Many experts are giving Louisville their flowers and picking them as college football's top sleepers, but with the Cardinals' schedule, it is a tall task.

Louisville has some challenging road games in 2025 as the Cardinals will face Pitt, Miami, Virginia Tech, and SMU. On top of that, they also have to face Clemson at home on a Friday night. For Louisville to make the CFP for the first time, Brohm must guide this Cardinals team to at least 10 wins and return to Charlotte.

Pick and choose how you may, but Louisville has to find a way to go 10-2 and beat some of the best ACC teams. If the Cardinals can go 11-1 (as some predict), then Louisville would go to Charlotte with a massive resume.

The Cardinals' offense has the skill and tools to guide this team to the College Football Playoffs. It will come down to the defense.

Related: Louisville 2025 game-by-game predictions: Can Cardinals beat Clemson again?

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