5 huge observations from Louisville football's gut-wrenching OT loss to Virginia

Louisville Cardinals fall to the Virginia Cavaliers in Overtime.
Matt Stone/Courier Journal / USA TODAY NETWORK via Imagn Images
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Louisville football's undefeated season is no more, as the Cardinals drop a heartbreaker in overtime to the Virginia Cavaliers. Louisville was a 6.5-point favorite entering this crucial ACC showdown, but with another slow start and more self-inflicted wounds, the Cards dropped their first game of the 2025 season.

This loss crushes the Louisville fans, as they are making it clear that this team has huge potential, but they consistently keep making the same mistakes. The Cardinals' path to the ACC Title just got a whole lot harder with the loss, as they now have to face Miami after their bye week, and then still have Clemson and SMU.

So, with Louisville dropping this game 30-27 in a crushing overtime loss, here are five immediate observations from the Cardinals' first loss of the 2025 season.

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