5 Louisville Cardinals who must step up after Isaac Brown's crushing injury update

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Louisville football received devastating news this morning that its star Isaac Brown will be out "for a while." The elite running back suffered an apparent leg injury in the fourth quarter that kept him sidelined for the remainder of the game, and Jeff Brohm announced this morning that he is out against Cal, and certainly made it seem like he might be out multiple games.

The Cards currently have the highest odds to make the College Football Playoffs out of any ACC team. So, with Louisville wanting to keep its playoff dreams alive, Brown's injury comes at the worst possible time. The true sophomore was flourishing and was finally emerging as his true self. He ran for 100 yards or more in three straight games, including his 205 rushing yard performance against Boston College.

However, now Louisville must find a way to win without its best player in the most crucial month of college football. Louisville has a Game this weekend, followed by Clemson, SMU, and Kentucky. The stakes are getting higher and higher each week, which means every player must step up now that Brown is out.

So, with Brown now officially out for Cal, and maybe more, here are five Louisville Cardinals who must step up after Isaac Brown's crushing injury update.

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