2. Keyjuan Brown
Louisville's rushing attack is the heart of this offense. Keyjuan Brown took a massive step this season as Isaac Brown and Duke Watson battled injuries all season long. The plan entering the offseason is to do whatever it takes to keep either Isaac or Keyjuan, and realistically, it will be hard to convince either to stay.
This isn't a lock, but it would be a massive blow if he does hit the portal. The Cardinals are going to have to throw a lot of money at one of these star running backs, and it just depends on who they pick. If Louisville can keep Isaac, it is reasonable to think Keyjuan would want to transfer out of Louisville and go play for another Power Four team, but start.
Keyjuan is second on the team in rushing yards with 592 yards on 81 carries. When he started for Louisville, he earned 29 carries for 271 rushing yards, proving he can be the No. 1 guy. It will be hard to keep any of the three-star running backs this offseason, and Louisville's recent three-game losing streak certainly doesn't help the Cardinals convince them to return.