The Louisville football program has their biggest test of the 2025 season so far, and they might be doing it with a thin locker room. Cardinals fans learned on Saturday that Louisville is without some key players, and their star running backs are still questionable.
Louisville fans have circled this game as a priority, as road games at Pitt have historically caused trouble for the Cardinals, with a 0-3 record on the road against Pitt since joining the ACC. All Louisville fans remember the heartbreaking loss in 2023 when the Cardinals were at the highest of highs, coming off a dominant win over No. 10 Notre Dame, but the Panthers thumped Louisville, putting an end to their undefeated season.
Now, Louisville looks to end this streak and earn its first road win at Pitt since joining the conference. The Cardinals aren't just due to beat Pitt tomorrow, though. These five reasons prove they will expose this 2-1 Panthers squad, cover the 4.5 points, and put the Louisville Cardinals on everyone's radar.
So, here are five reasons that proves the Louisville Cardinals will beat the Pittsburgh Panthers tomorrow afternoon.