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Louisville football vs. North Carolina early odds and a prediction

Louisville and Jeff Brohm look for their fifth straight win this weekend against UNC.
ByLuke Santangelo
IMAGN IMAGES via Reuters Connect

Louisville football is rolling right now as the Cardinals have rattled off four straight wins, including this past Saturday when UofL dominated Georgia Tech on the road. Louisville improves to 6-3 on the season and 5-2 in conference play after Louisville defeated the Yellow Jackets 44-17.

Now, the Cardinals will quickly turn their attention to their second straight road game, as Jeff Brohm and Louisville will face Bill Belichick and the North Carolina Tar Heels. UNC is currently sitting in 9th place in the ACC with a 5-4 record, but the Tar Heels are a team that can’t be taken lightly as they have played Notre Dame and Miami very closely.

Now, UofL will try to earn its fifth straight win and seventh win of the season. This marks the Cardinals' fourth road game of the season, with Louisville currently 2-1, including wins over Syracuse and Georgia Tech. With Week 10 in the rearview mirror, let’s look at early odds and predict this crucial November road showdown.

Louisville vs North Carolina early odds

The Cardinals enter this matchup as the slight favorite, according to ESPN Analytics and FanDuel. FanDuel lists the Cards as a slight favorite over the Tar Heels, as they are just a field-goal favorite over UNC, and the over/under is 60.5. As for ESPN Analytics, the Cardinals have a 60% chance to win this weekend.

Odds courtesy of FanDuel. 

Spread: Louisville -3.5

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Over/Under: 60.5

Moneyline: Louisville -166/North Carolina +140

Big Red Louie Predictions

Brohm and this Cardinals offense are really firing on all cylinders as we reach the final stretch of the season. The Cardinals offense has scored 40 points or more in three of its last four games and has scored 40 points or more in five games this season.

As for the Tar Heels, they enter this matchup after a 17-point win over UConn, but have lost their past two conference games, including a tight loss to Miami and a close 31-30 loss to Syracuse. The Tar Heels offense has recently found a spark, including scoring 35 at home against Miami and putting UNC in position to potentially upset the Hurricanes. The Tar Heels' defense is their biggest strength. This unit allows only 22 points per game and is well coached under Belichick.

However, we think Brohm and the Cardinals' offense are red-hot right now, and we predict a huge road win for UofL. We think Louisville will win this crucial game in mid-November, and we predict they'll cover the 3.5.

Prediction: Louisville 35 UNC 28

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