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Louisville football vs. North Carolina final odds and a prediction

Louisville looks to win their seventh game of the season.
ByLuke Santangelo
IMAGN IMAGES via Reuters Connect

Louisville football will take on North Carolina Saturday evening in a huge ACC matchup, as the 6-3 Cardinals travel to the 5-4 Tar Heels. Louisville remains in the hunt for the ACC Championship Game, as the Cardinals sit third in the conference behind Miami and Wake Forest.

3 bold predictions for Louisville vs. North Carolina in Week 11

Now, Louisville is looking to earn its fifth straight win, coming off a dominant 44-17 win over Georgia Tech. The Cardinals offense is firing on all cylinders, scoring 34 points or more in the past four games and 44 points or more in three of the four.

With game day here, Cardinals fans are eagerly waiting for this huge road matchup. Let’s break down the odds and make our game-day predictions.

Louisville vs North Carolina odds

Odds courtesy of FanDuel. 

Spread: Louisville -3.5

Over/Under: 57.5

Moneyline: Louisville -156/North Carolina +130

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Game odds refresh periodically and are subject to change.

How to watch Louisville vs. North Carolina in Week 11

  • Date: Saturday, November 14th
  • Time: 7:00 pm E.T.
  • Venue: Kenan Stadium
  • How to Watch (TV): ESPN 2
  • Streaming: fubo TV
  • Louisville record: 6-3
  • North Carolina record: 5-4

Big Red Louie Predictions

The Cardinals enter this matchup as a 3.5-point favorite, with ESPN Analytics slightly favoring Jeff Brohm at 60% to win. The Cardinals' biggest strength is their offense, which ranks No. 6 in the nation and averages 40.8 points per game, while North Carolina’s strength is its defense.

Despite sitting at 5-4, UNC has played No. 5 Notre Dame and No. 7 Miami very closely. This road matchup will be close, as the Tar Heels have proven they can compete with some of the best teams in the nation.

As for this game, a key to victory is the Cardinals dominating the run game and getting to the Tar Heels' quarterback. Louisville has two or more sacks in seven of their nine games and is coming off a dominant four-game sack against Georgia Tech. The Tar Heels have struggled to protect their QB, giving up three sacks to TCU, Pitt, and Clemson; two sacks to Duke and Syracuse; and a whopping four sacks to Miami.

As for the rushing attack, Louisville ranks No. 8 in the nation, averaging over 228 yards per game, and UNC has struggled to stop the run in their four losses. In three of those four losses, UNC gave up 120 yards or more to a single running back, including two games when they gave up 130 yards or more.

So, expect Louisville’s rushing attack and defensive line to be key tonight, which is why we predict a Louisville win.

Prediction: Louisville 31 North Carolina 27

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