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Louisville football vs Stanford final odds and a prediction

ByLuke Santangelo
IMAGN IMAGES via Reuters Connect

Louisville football will face the Stanford Cardinal for the second time in program history. Jeff Brohm and UofL are 0-1 as of right now, as Louisville lost to Stanford in 2024, when the Cardinals went to Stanford Stadium and won 38-35.

Louisville football vs. Stanford: how to watch, odds, injuries, more for Week 9 matchup

Now, they are trying to secure that first win against Stanford this afternoon inside L&N Stadium. UofL and Stanford are both on a two-game winning streak, with Stanford coming off an impressive win over North Carolina State and Louisville coming off wins over Florida State and Syracuse.

Louisville sits 4-3 and is fifth in the ACC. The Cardinals are eyeing a run the rest of the season, and that run starts this afternoon. So, with Louisville looking to win its fifth game of the season, let’s break down the odds and make some predictions.

How to watch Louisville vs. Stanford in Week 9

  • Date: Saturday, October 31st
  • Time: 3:15 pm E.T.
  • Venue: L&N Federal Credit Union Stadium
  • How to Watch (TV): ACC Network
  • Streaming: fubo TV
  • Louisville record: 4-3
  • Stanford record: 4-4

What are the betting odds for Louisville vs. Stanford?

Odds courtesy of FanDuel. 

Spread: Louisville -22.5

Over/Under: 60.5

Moneyline: Louisville -2000/Stanford +1000

Game odds refresh periodically and are subject to change.

Big Red Louie Predictions

Louisville football enters this game as the dominant favorite, with Jeff Brohm and the Cardinals favored by 22.5 points. Louisville will be without receiver Lawayne McCoy, but otherwise the Cardinals appear pretty healthy for this Week 9 showdown.

Stanford's key to upsetting Louisville is running back Micah Ford. He is second in the conference in rushing yards, with 679 yards on 136 carries and eight touchdowns. As for the Cardinals, this offense should be able to exploit this Cardinal defense, and Louisville should be able to run away with this one in the second half.

According to ESPN Analytics, Louisville has a 97.2 percent chance of winning and is favored by three touchdowns.We predict Louisville to earn its fifth win of the season, but we do think Stanford covers the 22.5.

Prediction: Louisville 38 Stanford 17

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