After Jeff Brohm's electric homecoming game and starting the season out 2-0 the Cards headed up North to Indianapolis to take on the Indiana Hoosiers in Lucas Oil Stadium. The Hoosiers led by coach Tom Allen had started the season 1-1, with a week 1 23-3 home loss to The Ohio State University and a 41-7 win over Indiana State at home in week 2.
Lucas Oil Stadium home of the Indianapolis Colts was the stage for this week 3 matchup. After a slow start to the game Louisville quarterback Jack Plummer connected a pass to wide receiver Jamari Thrash for a 85 yard touchdown. The Cards kept the momentum going with a Maurice Turner and Jawhar Jordan rushing touchdown to close out the half. Louisville was looking like they were going to run away with this one leading Indiana 21-0 at halftime.
Louisville came out of the locker room and struggled offensively in the second half. Indiana however was ready to fight back, and opened the half with a 30 yard touchdown pass from quarterback Tayven Jackson to running back Jaylin Lucas. The Cardinal offense and defense just couldn't come up with an answer. And with 1 minute left in the 3rd quarter Indiana running back Josh Henderson ran one in for a touchdown. Louisville was up 21-14 to start the 4th quarter. And with 4 minutes left the Hoosiers were knocking on the door 4th and goal at Louisville's 1 yard line. Louisville linebacker Stanquan Clark read the offense perfectly and helped complete the goal line stand that won Louisville the game. With that the Louisville Cardinals won the game 21-14 over the Indiana Hoosiers.
Quaterback Jack Plummer finished with 238 yards throwing for 1 touchdown and 1 interception. Running back Jawhar Jordan tallied 113 yards off of 18 carries and had 1 touchdown. While wide receiver Jamari Thrash recorded an impressive 159 yards on just 4 receptions and 1 touchdown. Louisville was off to a 3-0 start for the first time since the 2016 season. A promising start to what would turn out to be a great season for Jeff Brohm and his Louisville Cardinals.