In a Friday night showdown, Louisville and No. 2 Miami put on a show to start off a great weekend of college football. Miami was coming in as one of the few undefeated teams in the country, coming off a bye week after its biggest win of the season over FSU.
However, it seems like the week off still wasn't enough as the Cardinals were ready for everything the Hurricanes had to throw at them. Louisville was able to hold onto a thin lead throughout the game and seal it with an interception, the defense's fourth of the night. The Cardinals were able to upset the Hurricanes 24-21 to jump ahead of Miami in the ACC rankings.
LOUISVILLE UPSETS NO. 2 MIAMI 🔥
— SportsCenter (@SportsCenter) October 18, 2025
The Cardinals get their 2nd win vs. an AP-Top 2 team in school history 👏 pic.twitter.com/y5eSL1rNtO
Louisville completely exposed who Georgia always knew Carson Beck was by intercepting him four times, the last one being the biggest. Even though Miami made it close in the final eight minutes with a fumble and scoring a touchdown quickly, the Cardinals were able to take time off the clock and then trust the defense to get it done.
The Cardinal defense had the bend but don't break mindset late, and even though Miami was driving, when it mattered most, they got it done. Fans are ecstatic over the big upset win under Jeff Brohm and are showing it all over social media.
Louisville fans can't contain their excited over upset win over No. 2 Miami
Arguably the biggest win in Louisville football history. Jeff Brohm era. 🔥 pic.twitter.com/X7Vp4cXZHi
— L1C4‼️ (@LORCARDS) October 18, 2025
This is exactly why Louisville brought Brohm back to the program. Brohm now has a 4-2 record in games against a Top 5 team in the country. He has a record of winning, and it is showing with the Cardinals now.
FIRST ROAD WIN OVER A TOP 10 TEAM IN THE HISTORY OF LOUISVILLE FOOTBALL!!!!!!!!!
— Mike Rutherford (@CardChronicle) October 18, 2025
Louisville was always able to win at home, but to win on the road against a top team is something every program needs to be able to do, and now the Cardinals have proved they can do it.
The Louisville Cardinals upset the # 2 Miami Hurricanes in Miami!!! WOW!!! What a Game!!!! 😀😀😀!!!! #GoCards "This is College Football!" - Jeff Brohm!!!
— Trevor Rost (@TrevorRost6) October 18, 2025
An amazing quote from Brohm, this is what college football is all about.
This is why we brought Jeff Brohm home! Louisville Football baby! #GoCards 🔴⚫️ pic.twitter.com/CY9RvVWFTf
— Ian Herrington (@IanHerrington1) October 18, 2025
The Brohm era!
LOUISVILLE FOOTBALL BABY!!!!
— Aaliyah Rice (@uhleeyahrice) October 18, 2025
Say it louder for the people in the back.
at least Louisville football didn’t disappoint me like the Steelers 🥲
— Esmeralda (@BeYoutiful_E) October 18, 2025
There is a bright side to everything.
LOUISVILLE CARDINALS FOOTBALL!!! (I never doubted you). C-A-R-D-S, Cards Cards Cards!
— RedsBaseballFan (@Railroader2Ace) October 18, 2025
There may have been just a little bit of doubt at some points in the game, but in the end, the Cardinals came out on top, and that is what matters most.